Pharmacology

1. Study of the role of monocytes / macrophages in various inflammatory diseases
2. Study of the role and signalling mechanisms of the bitter taste receptor in the ectopic site, in particular in the epithelial and muscle cells of the lung, in skeletal muscle cells and in monocytes / macrophages
3. Isolation of stem cells from urine and differentiation into skeletal muscle cells for the identification of possible new drug targets for neuromuscular diseases

    

1. Talmon M et al., Cell Calcium 2022; 103:102548
2. Brambilla M et al., Int J Mol Sci. 2022 ;23(9):4811
3. Bertani D et al., Int J Mol Sci. 2021;22(24):13300
4. Talmon M et al., Bioorg Med Chem. 2020; 28(23):115760
5. Velnati S et al., Enzyme Inhib Med Chem. 2020; 35(1):96-108
6. Talmon M et al., J Nat Prod. 2020; 83(6):1740-1750
7. Talmon M et al., Pulm Pharmacol Ther. 2019; 59:101851
8. Talmon M et al., J Biol Chem. 2019; 294(33):12472-12482
9. Talmon M et al., Br J Pharmacol. 2018;175(1):113-124
10. Pollastro F et al., Curr Med Chem. 2018; 25(10):1160-1185

Prof.sa Francesca Boccafoschi (DiSS); Prof. Renzo Boldorini (DiSS); Prof.sa Ivana Rabbone (DiSS); Dott.ssa Anna Aspesi (DiSS); Prof Gianluca Baldanzi (DiMet); Prof Dmitry Lim (DSF); Prof.sa Federica Pollastro (DSF); Prof Alberto Minassi (DSF); Dr Maurizio Viri (Direttore di Neuropsichiatria Infantile AOU Maggiore della Carità di Novara); Dr Filippo Patrucco (Dirigente Medico Malattie Apparato Respiratorio AOU Maggiore della Carità di Novara); Prof.sa Marina Camera (Università di Milano); Dr Carlo Cattaneo (Dirigente Psichiatria presso ASL NOVARA); Prof Goutam Biswas (Assistant Professor Cooch Behar Panchanan Barma University, India); Dr. Angshuman Bagchi (University of Kalyani, India.

1. 2021 – Financial contribution by Boehringer Ingelheim Italia “Effects of anti-fibrotic drug nintedanib on human alveolar macrophages and blood monocytes in patients with Idiopathic Pulmonary Fibrosis (IPF) naïve for treatment.” (@LGF)
2. 2021 - Fondazione Roche per la Ricerca Indipendente "SNPs in the gene sequence of bitter taste receptors as predictive markers of asthma in children" (@MT)
3. 2019 - Fondi di Ateneo per la Ricerca (FAR, @ LGF/AA): “Effects of ribosomal stress on erythroid maturation”

Dott.ssa Luigia G. Fresu, Research Group Leader

Maria Talmon (Postdoc)